| | Conditions & Treatments | Muscle Strains What painkillers are best for pulled muscle? Over-the-counter (OTC) pain relievers, such as ibuprofen (Advil, Motrin IB) or acetaminophen (Tylenol, Panadol), can help to relieve pain and reduce inflammation. Muscle Strains - Related Articles Can you work out your jaw muscle? What is an example of a flexor muscle? Do men get more muscular or bulky with age? How to Stretch for a Rotator Cuff Tear Is irritability a function of muscle tissue? A DIY Foam Roller What controls smooth muscle movement?