Panphobia: The Fear of Everything—Causes, Symptoms, and Treatment

Panphobia (Omniphobia): Pervasive, Non-Specific Fear

Panphobia is an informal term for a condition where anxiety attaches to a constantly shifting array of objects, situations, and internal sensations—essentially "fear of fear itself." It is not a distinct DSM-5 diagnosis but may manifest as:

  • Generalized Anxiety Disorder (GAD) with extreme generalization.
  • Panic Disorder with agoraphobic avoidance.
  • Specific phobias that proliferate.
  • Somatic symptom disorder with health anxiety.

Symptoms

  • Persistent, free-floating anxiety.
  • Panic attacks triggered by minor stimuli.
  • Avoidance of multiple situations → severe functional impairment.
  • Hypervigilance, catastrophic misinterpretation of bodily sensations.

Etiology

  • Genetic predisposition + early trauma/stress.
  • Conditioned fear generalization.
  • Cognitive biases (intolerance of uncertainty, threat overestimation).

Treatment

  1. CBT with Exposure: Hierarchical exposure to avoided stimuli; cognitive restructuring.
  2. ACT (Acceptance and Commitment Therapy): Psychological flexibility.
  3. Medication: SSRIs/SNRIs first-line; short-term benzodiazepines only if severe.
  4. Mindfulness, exercise, sleep hygiene.

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