Synthyroid (Levothyroxine) & Food: Optimal Absorption & Timing

Synthyroid (levothyroxine) is a thyroid hormone replacement medication. It is typically taken on an empty stomach, 30 minutes to 1 hour before breakfast, to ensure that it is absorbed properly.

If you take Synthyroid with food, it can decrease the amount of thyroid hormone that your body absorbs. This can lead to lower thyroid hormone levels and decreased symptoms control. Taking Synthyroid with certain foods, such as dairy products, calcium-rich foods, or iron supplements, can also decrease its absorption.

Therefore, it is important to take Synthyroid on an empty stomach to ensure that it is absorbed properly and that you are getting the full benefit of the medication.

If you have difficulty taking Synthyroid on an empty stomach, talk to your doctor. They may recommend taking it with a small amount of water, or they may adjust your dose to compensate for the decreased absorption.