The Dermis: Structure and Function of the Skin's Middle Layer
The dermis is the thick, vascular, connective tissue layer between the epidermis and hypodermis (subcutis).
Composition
- Papillary dermis (superficial): Loose areolar CT, dermal papillae (interlock with epidermis), capillaries, Meissner's corpuscles (light touch).
- Reticular dermis (deep): Dense irregular CT, thick collagen/elastin bundles, hair follicles, sebaceous/sweat glands, Pacinian corpuscles (deep pressure), blood/lymph vessels, nerves.
Key Functions
- Structural support, elasticity, tensile strength
- Thermoregulation (vasodilation/constriction, sweating)
- Sensation (touch, pressure, pain, temperature)
- Nutrient supply to avascular epidermis
- Immune surveillance (dermal dendritic cells, mast cells)
- Appendage housing (hair, nails, glands)
Clinical Relevance
Wound healing (granulation tissue = new dermis), aging (collagen/elastin loss), scarring (dermal repair), dermatoses (psoriasis, eczema, neoplasia).
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