Persistent Black Patch on Hand: Differential and Urgency of Biopsy
A stable, round, black macule/patch >2 years warrants **dermatology evaluation** to exclude:
- Melanoma: Asymmetry, border irregularity, color variegation, diameter >6 mm, evolution (ABCDE). Even subtle changes need biopsy.
- Melanocytic nevus: Benign but may mimic melanoma.
- Seborrheic keratosis: Waxy, “stuck-on,” often pigmented.
- Dermatofibroma: Firm, dimple sign.
- Pigmented basal cell carcinoma
- Acral lentiginous melanoma (palm/sole/nail) — higher morbidity.
**Dermoscopy + biopsy** is standard. Do not delay; early melanoma is curable.
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