Persistent Black Patch on Hand: Differential and Urgency of Biopsy

A stable, round, black macule/patch >2 years warrants **dermatology evaluation** to exclude:

  • Melanoma: Asymmetry, border irregularity, color variegation, diameter >6 mm, evolution (ABCDE). Even subtle changes need biopsy.
  • Melanocytic nevus: Benign but may mimic melanoma.
  • Seborrheic keratosis: Waxy, “stuck-on,” often pigmented.
  • Dermatofibroma: Firm, dimple sign.
  • Pigmented basal cell carcinoma
  • Acral lentiginous melanoma (palm/sole/nail) — higher morbidity.

**Dermoscopy + biopsy** is standard. Do not delay; early melanoma is curable.

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