Ziana (Clindamycin/Tretinoin) Gel Cost: 2024 Pricing, Discounts & Savings

Ziana® (clindamycin phosphate 1.2% / tretinoin 0.025% gel) is a prescription topical for acne vulgaris.

2024 U.S. Pricing (30 g tube)

• Brand (Viatris): ~$600–$800 cash.
• Generic (clindamycin/tretinoin): ~$100–$250 cash (multiple manufacturers).
• With Insurance: Tier 2–3 copay $30–$75; prior auth often required.
• Discount Cards (GoodRx, SingleCare): $80–$150 generic; brand rarely discounted.
• Manufacturer Coupon: Viatris may offer $0 copay for eligible commercial patients (restrictions apply).

Cost-Saving Strategies

1. Request generic (AB-rated equivalents exist).
2. Compare pharmacies (Costco, HealthWarehouse, local independent).
3. Use GoodRx/Blink Health/SingleCare — show pharmacist.
4. Ask prescriber for samples.
5. Check patient assistance (Viatris Patient Assistance Program) if uninsured/low income.
6. Consider compounded clindamycin/tretinoin (lower cost, variable quality).

Clinical Context

• First-line for inflammatory + comedonal acne.
• Apply pea-sized amount nightly to clean, dry skin.
• Expect irritation (retinoid dermatitis) weeks 1–4; use moisturizer, alternate nights initially.
• Sun protection mandatory (tretinoin photosensitizes).

Prices fluctuate; verify at fill time. Generic is therapeutically equivalent and far more affordable.