Acute Alveolar Pneumonia: Definition and Pathophysiology
Acute alveolar pneumonia (synonymous with lobar pneumonia or pneumococcal pneumonia) is an acute infection of the pulmonary alveoli causing consolidation and loss of aeration.
Pathogenesis
- Pathogen (often Streptococcus pneumoniae) reaches alveoli.
- Inflammatory exudate (fibrin, neutrophils, RBCs) fills alveolar spaces.
- Consolidation → air bronchograms on imaging.
Classic Features
- Abrupt fever, rigors, pleuritic chest pain.
- Rust‑colored sputum.
- Bronchial breath sounds, crackles, increased tactile fremitus over consolidation.
Treatment
Empiric antibiotics per local guidelines (e.g., beta‑lactam ± macrolide/fluoroquinolone); supportive care.
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