A vs. B Antigens: Understanding ABO Blood Group Differences
A antigen:
- Produced by the A allele of the ABO blood group gene.
- Composed of N-acetylgalactosamine (GalNAc) attached to a core carbohydrate structure.
- Binds to anti-A antibodies.
B antigen:
- Produced by the B allele of the ABO blood group gene.
-Composed of D-galactose (Gal) attached to a core carbohydrate structure.
- Binds to anti-B antibodies.
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