Understanding Globulin Levels: Low or High?

Globulin levels that are too low or too high can indicate a variety of underlying health conditions. Low globulin levels can be caused by:

Liver disease: The liver produces globulins, so liver damage can lead to low globulin levels.

Kidney disease: The kidneys help regulate globulin levels, so kidney disease can lead to low globulin levels.

Malnutrition: A diet that is deficient in protein can lead to low globulin levels.

Certain medications: Some medications, such as corticosteroids, can lower globulin levels.

Certain medical conditions: Certain medical conditions, such as lupus and rheumatoid arthritis, can lead to low globulin levels.

High globulin levels can be caused by:

Infections: Infections can cause globulin levels to increase as the body produces antibodies to fight off the infection.

Certain medical conditions: Certain medical conditions, such as multiple myeloma and Waldenström macroglobulinemia, can lead to high globulin levels.

Autoimmune diseases: Autoimmune diseases, such as lupus and rheumatoid arthritis, can lead to high globulin levels.

If your globulin levels are abnormal, it is important to see your doctor to determine the cause and receive appropriate treatment.