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Biliary System: Anatomy, Function, and Common Disorders

Biliary pertains to the bile ducts, gallbladder, and bile.

Anatomy & Physiology

  • Liver produces bile → hepatic ducts → common hepatic duct.
  • Cystic duct ↔ gallbladder (storage/concentration).
  • Common bile duct → duodenum (major papilla, shared with pancreatic duct).
  • Bile: bile salts (emulsify fats), bilirubin (excretion), cholesterol.

Common Disorders

  • Cholelithiasis – gallstones (cholesterol or pigment).
  • Choledocholithiasis – stones in CBD.
  • Cholangitis – biliary infection (Charcot's triad: pain, fever, jaundice).
  • Biliary atresia – neonatal obliteration of extrahepatic ducts.
  • Primary sclerosing cholangitis (PSC) – inflammatory stricturing.
  • Gallbladder cancer – rare, associated with stones/porcelain GB.

Diagnosis: ultrasound (first‑line), MRCP, ERCP, HIDA scan.

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