Esophageal Pedunculated Polyp: Symptoms, Diagnosis & Treatment Options

A pedunculated esophageal polyp is a mucosal projection on a stalk (peduncle), usually benign (fibrovascular, inflammatory, hyperplastic). Rarely: adenomatous (premalignant) or squamous cell carcinoma.

Symptoms (Size/Location Dependent)

  • Dysphagia (mechanical obstruction).
  • Globus sensation.
  • Regurgitation, heartburn (if near LES).
  • Chest pain (esophageal spasm).
  • Bleeding (ulcerated surface) → hematemesis/melena.
  • Asymptomatic (incidental on endoscopy).

Diagnosis

  • Upper endoscopy (EGD): Visualizes polyp, stalk, mobility.
  • Biopsy: Mandatory—rules out dysplasia/carcinoma.
  • EUS: Assesses wall layer origin, depth, lymph nodes.

Treatment

  • Endoscopic resection: Snare polypectomy (pedunculated), EMR/ESD (sessile/large). En bloc preferred.
  • Surgery: If malignant invasion, failed endoscopic resection, or perforation.
  • Surveillance: If benign, small, asymptomatic—interval endoscopy per guidelines.

Follow-Up

Pathology dictates surveillance. Benign: 1–3 years. Dysplasia/cancer: multidisciplinary, per oncology guidelines.

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