Skelaxin (Metaxalone) and Surgery: 48-Hour Pre-op / 24-Hour Post-op Hold

Critical Warning: Do not take metaxalone (Skelaxin) within 48 hours before or 24 hours after surgery involving general or spinal anesthesia.

Concurrent use can potentiate central nervous system depression, leading to serious respiratory depression or apnea in susceptible individuals.

Inform your surgeon and anesthesiologist of all medications, including muscle relaxants, during preoperative assessment.