MRSA and Staphylococcus aureus: Gram-Positive Bacteria Explained

MRSA = methicillin-resistant Staphylococcus aureus. S. aureus is a Gram-positive bacterium—it retains crystal violet stain due to its thick peptidoglycan cell wall. MRSA strains have acquired the mecA gene (or mecC), encoding an altered penicillin-binding protein (PBP2a) that confers resistance to beta-lactam antibiotics including methicillin, oxacillin, and most cephalosporins.

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