Neonatal Lactose Intolerance: Causes, Symptoms, and Management

Lactose intolerance can occur in newborns when the body cannot fully digest lactose, the primary sugar in milk. The most common cause is lactase enzyme deficiency, which may stem from genetics, medical conditions, or premature birth.

Symptoms

• Diarrhea
• Abdominal bloating and gas
• Excessive crying and fussiness
• Poor weight gain
• Acid reflux

Management

If lactose intolerance is suspected, a healthcare provider may recommend reducing or eliminating dairy. In severe cases, specialized formula may be needed. Note that this differs from cow's milk protein allergy, which is an immune reaction to milk proteins.