Hemophilia Inheritance: Understanding the Risk for Children

Hemophilia is an X-linked recessive disorder. In the scenario where the mother has hemophilia (genotype X^hX^h) and the father is unaffected (X^HY):

• Sons inherit the father's Y chromosome and one of the mother's affected X chromosomes, resulting in genotype X^hY. They will have hemophilia.
• Daughters inherit the father's normal X^H and one of the mother's X^h, becoming carriers (X^HX^h) but typically asymptomatic.

Therefore, there is a 100% chance each son will have hemophilia, and a 100% chance each daughter will be a carrier. The original statement claiming 0% chance is incorrect for this parental genotype combination.