Colorblindness Inheritance: Predicting Daughter Carrier Status
A colorblind father and normal sighted homozygous mother can produce daughter that is carrier. Here's the detailed explanation:
Let's use the following alleles to represent the genes involved:
- C: Normal vision allele (dominant)
- c: Colorblindness allele (recessive)
Since the father is colorblind, he must have two copies of the c allele (cc). The mother is normal sighted and homozygous, meaning she has two copies of the C allele (CC).
When the colorblind father (cc) and normal sighted homozygous mother (CC) have children, all of their daughters will be carriers. This is because the daughters will inherit one C allele from their mother and one c allele from their father.
Here's how the genotypes of the parents and daughter would look like:
Parents:
- Father: cc (colorblind)
- Mother: CC (normal sighted, homozygous)
Daughter:
- Carrier: Cc (normal vision, carrier)
The daughter will have normal vision because she has at least one copy of the dominant C allele. However, she will also carry the recessive c allele, which means she can pass it on to her children. If she has children with a colorblind male (cc), there is a 50% chance that their male children will be colorblind and a 50% chance that their female children will be carriers.
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