Tamiflu (Oseltamivir) Capsules: Why They Must Be Swallowed Whole

Do not open, crush, or chew Tamiflu capsules.

Reasons

• Alters pharmacokinetics—may affect absorption, safety, efficacy.
• Powder inhalation risk → respiratory irritation.
• Bitter taste; poor adherence if mixed.
• Manufacturer instructions explicitly prohibit opening.

Alternatives for Swallowing Difficulty

• Tamiflu oral suspension (6 mg/mL) – can be compounded by pharmacy.
• Discuss with prescriber for appropriate formulation.

Always follow labeled administration instructions.