Stilnox (Zolpidem) and Juice/Milk: Important Interactions & Safety

Stilnox (zolpidem) is a prescription medication used to treat insomnia. It belongs to the class of drugs known as nonbenzodiazepine hypnotics. It is mainly used to induce sleep in the short-term.

Mixing Zolpidem with Fruit Juice:

- ZOLPIDEM is highly protein-bound and has a high volume of distribution.

- The plasma concentrations of zolpidem significantly decreased after administration with grapefruit juice.

- Avoid taking ZOLPIDEM within 2 hours before or 2 hours after consuming grapefruit juice.

Mixing Zolpidem with Dairy Products:

- Zolpidem is highly bound to plasma protein.

- Coadministration of zolpidem with milk was reported to slightly decrease zolpidem clearance and slightly prolong its half-life.

- The clinical significance of these effects is unknown; caution is advised when zolpidem is used concomitantly with milk.

To ensure safe and effective medication use, it is important to follow the dosing and administration instructions provided by your doctor or pharmacist. Please consult with your healthcare provider if you have any questions or concerns about taking Stilnox with specific beverages.