Smallpox Transmission: How the Disease Spreads - Causes & Prevention

The mode of transmission for smallpox is through close contact with an infected person or through contact with contaminated objects. The virus is spread through the air when an infected person coughs, sneezes, or talks. It can also be spread through contact with infected skin lesions or through contact with contaminated clothing or bedding. Smallpox is highly contagious, and it can spread easily among people who are not vaccinated.