Shingles Vaccine: Recommended Age, Eligibility, and Timing

Shingrix (recombinant zoster vaccine) is the preferred vaccine (replaced Zostavax in 2020).

Standard Recommendation

• Age ≥50: Two doses, 2-6 months apart.
• Age ≥19 with immunocompromise: Two doses, 1-2 months apart (HIV, transplant, chemo, biologics, etc.).

Special Considerations

• Prior Zostavax: Wait ≥8 weeks, then give Shingrix 2-dose series.
• Prior shingles: Vaccinate after acute episode resolves; reduces recurrence.
• Pregnancy/breastfeeding: Delay until after; no safety data.
• Acute illness: Defer until recovery.

Efficacy & Safety

• >90% effective against shingles and PHN across age groups.
• Common reactions: injection site pain, myalgia, fatigue, headache (1-3 days).
• No live virus—safe for immunocompromised.

Access

Covered by Medicare Part D, most private insurance. Pharmacies and clinics administer. No prescription needed in most states.