Triptans for Migraines: Long-Term Effects & Considerations

Triptans are a class of drugs called serotonin receptor agonists. They are used for the treatment of migraine headaches. Their effectiveness must be balanced with their potential side effects.

Function

• Triptans relieve migraine symptoms by reducing the size of blood vessels in the brain and alleviating swelling.

Effectiveness

• Generally, triptans treat migraines well, especially if taken at the onset of the headache. A trial-and-error approach is used to determine which triptan drug is best. A triptan which alleviates pain for one person may not be effective for another.

Side Effects

• When taken as directed, triptans produce side effects such as tingling, dizziness, drowsiness, weakness and a bitter taste in throat.

Long-Term Effects

• Taking triptans for an extended period of time can produce a chronic condition called rebound headaches. It is an intense headache which occurs after the triptan has worn off. It can lead to dependency on triptans or other pain medication.

Considerations

• If you are allergic to triptans or are taking SSRIs or SNRIs, avoid using a triptan. If you have heart conditions, liver problems or a history of strokes, triptans may not be suitable for you.