Cold Sores (Fever Blisters): Effective Treatments vs. What Doesn't Work

Nystatin/triamcinolone cream is ineffective for cold sores. This combo treats fungal skin infections (athlete's foot, jock itch). Nystatin is antifungal; triamcinolone is a corticosteroid.

Correct Treatment

Cold sores are caused by herpes simplex virus (HSV). Antivirals are standard:

  • Oral: acyclovir, valacyclovir, famciclovir.
  • Topical: acyclovir, penciclovir creams or patches.

These inhibit viral replication, reducing severity and duration.

See a healthcare provider for accurate diagnosis (cold sores can mimic other conditions) and prescription.

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