Akinetic Seizures (Drop Attacks): Sudden Loss of Muscle Tone

Akinetic seizures (astatic/drop seizures) feature abrupt loss of postural tone without impaired consciousness.

  • Patient suddenly collapses (head drop, knee buckling, full fall)
  • Duration: seconds
  • Rapid recovery, no postictal confusion
  • Often part of Lennox-Gastaut syndrome or other epileptic encephalopathies

Differential: cataplexy (emotion-triggered, conscious), syncope (prodrome, pallor), atonic seizures (same, but term "akinetic" emphasizes motor arrest).

Video-EEG confirms diagnosis; treatment includes valproate, lamotrigine, rufinamide, ketogenic diet, VNS.

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