Skeletal vs. Cardiac Muscle Excitation & Inhibition: A Comparative Analysis
Excitation
* Skeletal muscle: Acetylcholine (ACh) released from motor neurons
* Cardiac muscle: Calcium ions (Ca2+) released from the sarcoplasmic reticulum
Inhibition
* Skeletal muscle: None
* Cardiac muscle: Hyperpolarization of the cell membrane, which can be caused by a number of factors, including the release of acetylcholine from parasympathetic nerves
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