Is there any danger when taking methadone and also fioricet for migraines?

Yes, there is a danger when taking methadone and also Fioricet for migraines.

Fioricet contains butalbital, which is a barbiturate. Methadone is also a central nervous system depressant. When taken together, these two drugs can cause respiratory depression, which can be fatal.

In addition, Fioricet can also cause drowsiness, dizziness, and impaired coordination. These side effects can be exacerbated when taken with methadone.

For these reasons, it is important to talk to your doctor before taking Fioricet if you are also taking methadone. Your doctor can weigh the risks and benefits of taking these two drugs together and make sure that you are taking them safely.