Lyme Disease Endemic Regions: Europe, North America, and Asia Risk Areas

Lyme borreliosis (Borrelia burgdorferi sensu lato) is the most common vector-borne disease in the Northern Hemisphere, transmitted by Ixodes ticks.

Geographic Distribution

  • Europe: Endemic in most countries; highest incidence in Central/Eastern Europe (Austria, Czechia, Germany, Slovenia, Baltic states, Scandinavia). UK: rising, especially Scotland.
  • North America: Northeast, Mid-Atlantic, Upper Midwest (US); southeastern Canada (Nova Scotia, Quebec, Ontario, Manitoba). B. burgdorferi s.s. dominant.
  • Asia: China (NE, NW), Japan (Hokkaido), Korea, Russia (Siberia, Far East), Mongolia. Species: B. garinii, B. afzelii, B. bavariensis.

Risk Modifiers

  • Season: Peak nymphal activity May–July (highest human risk).
  • Habitat: Deciduous woods, leaf litter, ecotones.
  • Host density: White-footed mice (US), rodents/birds (Europe/Asia).

Prevention

  • Permethrin-treated clothing, EPA-registered repellents (DEET ≥20%, picaridin, IR3535).
  • Daily tick checks; prompt removal (<24 hrs attachment).
  • Landscaping: barriers, deer fencing, acaricide treatment.

Post-exposure prophylaxis (doxycycline 200 mg single dose) if high-risk bite in endemic area.

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