Autopsy Findings in Essential Hypertension: Kidney Pathology & Characteristics
Autopsy Findings in Essential Hypertension Kidney
* Gross
* Kidneys are typically enlarged and firm, with a red or purple appearance.
* The renal capsule may be thickened and adherent to the underlying parenchyma.
* On cut surface, the cortex may be thin and pale, while the medulla may be congested.
* There may be evidence of arteriolosclerosis and interstitial fibrosis.
* Microscopic
* The glomeruli may show evidence of hypertrophy, sclerosis, and/or necrosis.
* The renal tubules may be atrophic and may contain protein casts.
* The interstitium may be fibrotic and may contain inflammatory infiltrates.
* The arteries and arterioles may show evidence of arteriosclerosis, with thickening of the intima and media.
* Immunofluorescence
* Immunofluorescence staining may reveal the presence of immune complexes in the glomeruli.
* Electron Microscopy
* Electron microscopy may reveal changes in the basement membrane of the glomeruli and renal tubules.
Kidney Disease - Related Articles
- Acute Kidney Failure: Symptoms, Causes & What to Do
- Kidney Scar Tissue: Understanding Causes, Progression, and Management
- The Vital Role of Kidneys in Maintaining Blood Volume and Fluid Balance
- Kidney Stone Size & Passage: What You Need to Know
- Chronic Kidney Disease vs. Renal Disease: Understanding the Differences
- Acute Kidney Failure: Symptoms, Causes & What to Do
- Infantile Polycystic Kidney Disease (PKD): Causes & Symptoms