Alpha Blockers vs. Alpha-Adrenergic Blockers: Understanding the Difference

Alpha blocker and alpha-adrenergic blocker are synonymous. They block adrenaline (epinephrine) effects, used for hypertension, heart failure, BPH, Raynaud's, angina.

Mechanism

Block adrenaline-induced vasoconstriction and tachycardia, lowering blood pressure and heart rate.

Types

• Selective alpha1-blockers: Target alpha1-receptors (vessels, heart).
• Non-selective alpha-blockers: Block alpha1 and alpha2 (central nervous system).

Side Effects

Dizziness, lightheadedness, headache, fatigue, nausea, GI upset, dry mouth, blurred vision, nasal congestion.

Contraindications

Severe allergies, syncope history, orthostatic hypotension, heart failure, prostate cancer.

Risks

Sudden hypotension (syncope), heart failure, stroke, MI, renal/hepatic failure, death. Discuss risks/benefits with your doctor.