Testosterone Patches for Fertility: Addressing Infertility in Advanced Maternal Age

The link between advanced maternal age and infertility is well-researched and generally acknowledged universally. Fortunately, a number of promising options exist for individuals dealing with fertility issues. One advancement is androgen-based therapy --- specifically, treating infertility with testosterone.

Effects

• Research of the use of testosterone patches, or transdermal testosterone therapy, has primarily focused on women undergoing in vitro fertilization. However, the information gained from this research is also applicable to those attempting traditional fertilization. Testosterone is thought to stimulate the ovaries by augmenting their responsiveness to certain hormones integral to the process of becoming pregnant --- namely, follicle-stimulating hormone, or FSH.

Considerations

• Androgen-based therapy carries possible side effects. For instance, transdermal testoterone may affect bone density, muscle formation and overall body weight, as well as have sexual side effects. A decision on whether to use this therapy is best reached after careful collaboration with your health care provider.

Best Candidates

• This type of therapy has proved most effective in women who have exhibited a low follicular response. For these patients, this approach may prove the best treatment, whereas in others, its risks and adverse effects may outweigh its benefits.