Fertility Assessment: Pregnancy Chances with E2, FSH, and LH Levels at 46

It is unlikely to become pregnant with the provided hormone levels.

The estradiol (E2) level of 126 pg/mL is relatively low, which is more typical during the follicular phase of the menstrual cycle rather than during the ovulatory phase. For ovulation to occur, E2 levels typically rise to around 150-300 pg/mL.

The follicle-stimulating hormone (FSH) level of 7.8 mIU/mL is within the normal range for your age, indicating that your ovaries are still somewhat responsive to FSH. However, FSH levels tend to increase with age, and higher FSH levels can indicate a decline in ovarian function.

The luteinizing hormone (LH) level of 4.2 mIU/mL is also relatively low and is not typically sufficient to trigger ovulation. Normally, a significant increase in LH, known as the LH surge, occurs before ovulation.

Additionally, the age of 46 is associated with a significant decline in fertility due to a decrease in the number and quality of eggs.

Therefore, it is less likely that you will be able to become pregnant with the provided hormone levels at age 46. If you are planning to conceive, it would be advisable to consult with a reproductive endocrinologist to evaluate your fertility and discuss potential options.