Understanding Male Hormones: Testosterone, DHT, and Androstadienedione

Predominant male hormones: testosterone, dihydrotestosterone (DHT), and androstadienedione. They drive development/maintenance of male reproductive structures and secondary sexual characteristics.

  • Testosterone: Primary male sex hormone from testes. Develops genitalia, deep voice, facial hair, muscle mass. Affects libido, energy.
  • DHT: Derived from testosterone via 5-alpha-reductase. Active form in prostate, hair follicles, sebaceous glands. Essential for penis, prostate, external genitalia development in puberty. Role in male pattern baldness and benign prostatic hyperplasia.
  • Androstadienedione: From testes/adrenals. Less potent but convertible to testosterone/DHT. Maintains libido and sexual function.

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