Blood Pressure and Kidney Function: How Hypertension and Hypotension Affect GFR

Glomerular filtration rate (GFR) measures kidney filtering capacity. Blood pressure directly influences GFR:

  • Hypertension: Chronic high pressure damages renal vessels, causing scarring, nephron loss, decreased GFR, and eventual kidney failure.
  • Hypotension: Low pressure reduces renal perfusion, starving nephrons of blood, also decreasing GFR.

Maintaining blood pressure within a healthy range is crucial for preserving kidney function and preventing chronic kidney disease.

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