Viral Hemorrhagic Fever Diagnosis: Key Diagnostic Methods

Definitive diagnosis of viral hemorrhagic fever rests on:

• Characteristic signs and symptoms (e.g., high fever, hemorrhagic manifestations, multi-organ failure).

• Laboratory findings suggestive of the disease (e.g., cytopenias, elevated liver enzymes, and signs of impaired renal function).

• Positive serological tests (e.g., ELISA, immunofluorescence assay, virus neutralization test).

• Reverse transcriptase polymerase chain reaction (RT-PCR) for detection of the specific viral RNA.