| | Conditions & Treatments | Heartburn & GERD Is the lub systolic or diastolic? The 'lub' heart sound corresponds to the closure of the mitral and tricuspid valves (between the atria and ventricles) at the start of systole. Heartburn & GERD - Related Articles Food to Avoid for Acid Reflux Natural Heartburn Remedy How to Use Sugar to Cut Acidity Use of Cisapride Gastroesophageal Reflux in Infants & Children Sodium Bicarbonate for Acid Reflux Does thrush show up on a rapid strep test?