Glycerin Suppositories for Constipation: Mechanism, Usage, and Precautions

Mechanism

Glycerin is a hyperosmotic agent: draws water into rectal lumen → softens stool, stimulates rectal stretch receptors → defecation reflex.

Step-by-Step Use

1. Wash hands.
2. Remove wrapper.
3. Lie on left side, knees flexed.
4. Insert pointed end gently into rectum.
5. Retain for few minutes.
6. Walk around to stimulate urge.

Onset and Frequency

Works in 15–30 minutes. Max 2 suppositories/24 hrs.

Contraindications/Precautions

• Rectal bleeding, fissures, prolapse, recent rectal surgery.
• Heart/kidney disease (fluid shifts) – consult doctor.
• Not for long-term use; addresses symptom, not cause.

When to See a Doctor

No BM after 2 doses, persistent constipation, abdominal pain, blood in stool, weight loss.