The Heart & Circulatory System: A Vital Interdependence
The heart and circulatory system form an integrated cardiovascular system. The heart depends on the vasculature for:
- Coronary perfusion – oxygen/nutrient delivery to myocardium via coronary arteries (from aortic root).
- Preload – venous return (via SVC/IVC) fills atria; determines stroke volume (Frank-Starling).
- Afterload – systemic vascular resistance against which LV ejects; affects myocardial O₂ demand.
- Neurohormonal regulation – baroreceptors, RAAS, catecholamines modulate rate/contractility.
- Metabolic waste removal – coronary venous drainage → coronary sinus → right atrium.
Conversely, the heart drives circulation via rhythmic contraction. Failure of either component compromises the other (e.g., heart failure → venous congestion, renal hypoperfusion; vascular disease → ischemia → pump failure).
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