Chamomile and Graves' Disease: What the Science Says

There is no clinical evidence that chamomile (Matricaria chamomilla) treats Graves' disease (autoimmune hyperthyroidism).

Graves' Disease Pathophysiology

• TSH receptor antibodies (TRAb) stimulate thyroid → excess T3/T4.
• Treatment: Antithyroid drugs (methimazole, PTU), radioactive iodine, thyroidectomy.
• Beta-blockers for symptom control.

Chamomile Properties

• Apigenin, bisabolol, chamazulene – anti-inflammatory, anxiolytic, mild sedative.
• May help anxiety, insomnia, GI upset – symptoms of hyperthyroidism.
• No effect on TRAb, thyroid hormone synthesis, or thyroid autoimmunity.

Risks

• Allergy (Asteraceae family: ragweed, chrysanthemum).
• Drug interactions: anticoagulants (warfarin), sedatives, CYP450 substrates.
• Not a substitute for evidence-based therapy.

Integrative Approach

Chamomile tea may complement conventional treatment for symptom relief (anxiety, sleep) but never replaces antithyroid medication, RAI, or surgery. Discuss with endocrinologist.