hCG Levels & Pregnancy: How Far Along Are You?
Serum β-hCG correlates roughly with gestational age but varies widely. Levels typically double every 48–72 hours in early viable pregnancy.
Reference Ranges (from LMP)
| Weeks | hCG (mIU/mL) |
|---|---|
| 3 | 5–50 |
| 4 | 50–400 |
| 5 | 100–5,000 |
| 6 | 1,000–10,000 |
| 7–8 | 10,000–100,000 |
An hCG of 137 mIU/mL suggests ~4 weeks 2 days, but a single value cannot date pregnancy. Serial measurements and transvaginal ultrasound (≥1,500–2,000 mIU/mL discriminatory zone) are required for accurate dating and viability assessment.
Clinical Pearls
- Ectopic pregnancy: slower rise, plateau, or decline.
- Molar pregnancy: excessively high levels.
- Multiple gestation: higher levels for dates.
Always correlate with clinical context and imaging.
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