Chlamydia Treatment Requires Confirmed Diagnosis First

Antibiotics for Chlamydia trachomatis must follow a positive NAAT. Empiric treatment without testing risks:

  • Missed co-infections (gonorrhea, trichomonas, MG)
  • Unnecessary antibiotic exposure (resistance, microbiome disruption)
  • False reassurance if symptoms from other cause
  • Partner notification failure

Expedited partner therapy (EPT) is permitted in many jurisdictions after index case confirmation. Test → treat → retest at 3 months.

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