White Blood Cells: The Body's Defense Force

White blood cells (leukocytes) are the cellular effectors of innate and adaptive immunity.

Major Types & Functions

  • Neutrophils: First responders; phagocytosis, NETosis.
  • Lymphocytes: B cells (antibodies), T cells (cellular immunity), NK cells (innate cytotoxicity).
  • Monocytes/Macrophages: Phagocytosis, antigen presentation, cytokine production.
  • Eosinophils: Parasites, allergic inflammation.
  • Basophils/Mast cells: Immediate hypersensitivity, histamine release.

Leukocytosis (>11,000/µL) suggests infection, inflammation, stress, or malignancy. Leukopenia (<4,000) risks infection.

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