O- Blood Type: Prevalence, Statistics & Geographic Distribution

O-negative (O-) blood type prevalence varies significantly by ancestry and geography:

  • United States: ~7% of population
  • Europe: ~6% (higher in Basques, Celts, Scandinavians)
  • Asia: ~1–3% (very rare in East Asia)
  • Africa: ~3–5% (varies by region)
  • Indigenous Americas: Higher frequencies in some groups

Clinical Significance

  • Universal red cell donor: O- RBCs can be transfused to any blood type in emergencies.
  • Universal plasma recipient: Can only receive O- plasma.
  • Critical for trauma, neonates, and immunocompromised patients.
  • Chronic shortage: High demand, low supply—O- donors are especially encouraged to donate regularly.

Blood type is genetically determined (ABO and Rh genes). Knowing your type aids emergency preparedness and donation eligibility.

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