Non-Radiographic Axial Spondyloarthritis (nr-axSpA) to Axial Spondyloarthritis (axSpA): Understanding the Progression

Nonradiographic axial spondyloarthritis (nr-axSpA) is a type of inflammatory arthritis that affects the spine and can lead to pain, stiffness, and disability.

In some cases, nr-axSpA can progress to radiographic axial spondyloarthritis (axSpA), which is a more advanced form of the disease that is characterized by damage to the spine that can be seen on X-rays.

The risk of progression from nr-axSpA to axSpA is not fully understood, but some factors that may increase the risk include:

- Male sex

- Younger age at onset of symptoms

- Presence of certain genetic markers

- High levels of inflammation

If you have nr-axSpA, your doctor may recommend regular monitoring to check for signs of progression to axSpA. This may include periodic X-rays and blood tests.

Early diagnosis and treatment of nr-axSpA can help to slow or prevent the progression to axSpA and reduce the risk of developing complications.