T3 and T4 Production: The Role of Thyroid-Stimulating Hormone (TSH)

The thyroid gland’s production of triiodothyronine (T3) and thyroxine (T4) is driven by a precise hormonal signal.

Thyroid-stimulating hormone (TSH), also called thyrotropin, is released from the anterior pituitary. It binds to TSH receptors on thyroid follicular cells, stimulating the synthesis and secretion of both T3 and T4. This feedback loop helps regulate metabolism, growth, and energy balance throughout the body.