Understanding Abnormal Testicles: Symptoms, Causes & What to Do

Any change in testicular size, shape, consistency, or sensation warrants medical evaluation. Early detection is critical—especially for testicular cancer, the most common solid malignancy in men 15–35.

Signs & Symptoms

  • Size change: One testicle noticeably larger/smaller.
  • Shape irregularity: Nodules, flattening, asymmetry.
  • Consistency change: Hardness, firmness, rubbery feel.
  • Pain/discomfort: Dull ache, heaviness, sharp pain (torsion = emergency).
  • Scrotal swelling/lump: Hydrocele, spermatocele, hernia, tumor.
  • Gynecomastia/nipple discharge: Rare; hCG-secreting germ cell tumors.
  • Back/abdominal pain: Late sign of metastatic spread.

Common Causes

Diagnostic Workup

  1. History & physical exam (including transillumination).
  2. Scrotal ultrasound (first-line imaging).
  3. Tumor markers: AFP, hCG, LDH (if mass suspicious).
  4. MRI/CT if staging needed.

Self-Exam & Action

  • Monthly testicular self-exam (after warm shower).
  • Any abnormality → see a doctor immediately. Do not wait.

Most testicular conditions are treatable—especially cancer (>95% cure if localized). Delay is the enemy.

Testicular Cancer - Related Articles

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ConditionKey FeaturesUrgency
Testicular cancerPainless hard lump; 95% germ cell tumorsHigh — urgent urology referral
EpididymitisPainful, swollen epididymis; often STI (chlamydia/gonorrhea) or UTIPrompt — antibiotics
Testicular torsionSudden severe pain, high-riding testis, absent cremasteric reflexEmergency — surgery <6 hrs
HydrocelePainless fluid-filled scrotal swelling; transilluminatesLow — observe or repair if large
Varicocele"Bag of worms" feel; left-sided; may affect fertilityElective — repair if symptomatic/infertility
SpermatoceleCyst on epididymis; benign, transilluminatesLow — observe
Undescended testisAbsent from scrotum; cancer risk if not orchiopexy'dPediatric — surgery by 18 mo