Epigastric Region: Anatomic Boundaries and Contents

The epigastric region is the upper central abdominal quadrant, bounded:

• Superiorly: xiphoid process
• Inferiorly: umbilical plane (transpyloric)
• Laterally: costal margins (midclavicular lines)

Contents: Stomach, liver (left lobe), pancreas (body/tail), duodenum (proximal), abdominal aorta, celiac plexus.

Epigastric pain suggests gastritis, peptic ulcer, pancreatitis, biliary colic, myocardial infarction (referred), or aortic pathology. Localization guides differential.