What Is Advanced Basal Cell Carcinoma?

Advanced basal cell carcinoma (BCC) refers to a type of non-melanoma skin cancer that has grown locally or spread to other parts of the body. It is an aggressive subtype of basal cell carcinoma, which typically arises from the overgrowth of basal cells, the cells that make up the deepest layer of the skin.

Unlike typical BCCs that often appear as pearly or waxy bumps on sun-exposed areas of the skin, advanced BCCs can display more complex and aggressive behavior:

1. Locally Advanced BCC: Locally advanced BCCs have grown beyond the initial site and invaded deeper tissues, such as muscles, bones, or nerves. They may appear as larger lesions, develop irregular borders, or ulcerate.

2. Metastatic BCC: Metastatic BCC is a rare but severe form where the cancer cells spread to distant parts of the body, such as lymph nodes, lungs, or bones, through the lymphatic system or bloodstream. This type of BCC is more likely to occur in individuals with weakened immune systems or underlying medical conditions.

3. Recurrent BCC: Advanced BCCs can also be recurrent, meaning they reappear after previous treatment. Recurrent BCCs may be more difficult to treat and require alternative treatment strategies.

Advanced BCC is less common compared to early-stage BCC, and it's important to recognize and seek prompt medical attention for any changes in skin lesions or suspicious growths. Early diagnosis and appropriate treatment can effectively manage advanced BCC and improve outcomes.