Enlarged Liver (Hepatomegaly): Symptoms, Causes, and When to Seek Care

Common Symptoms

• Abdominal pain/discomfort in upper right quadrant (worsens after meals)
• Abdominal swelling/distension
• Jaundice (yellowing of skin/eyes)
• Dark urine
• Pale or clay-colored stools
• Nausea and vomiting
• Loss of appetite
• Fatigue and weakness
• Itchy skin (cholestasis)
• Fever (suggests infection/inflammation)
• Weight loss

Important Notes

• Early hepatomegaly may be asymptomatic, detected only on routine exam or blood tests.
• Symptoms vary by underlying cause and severity.

If you experience any of these, see a healthcare provider for evaluation, diagnosis, and treatment.