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Leukocytes: Diverse Types, Mobility, and Key Immune Functions

Major Leukocyte Types

  • Neutrophils: First responders; phagocytosis, NETosis.
  • Lymphocytes: B cells (antibodies), T cells (cell-mediated), NK cells (innate cytotoxicity).
  • Monocytes/Macrophages: Phagocytosis, antigen presentation, tissue repair.
  • Eosinophils: Anti-parasitic, allergic inflammation.
  • Basophils: Histamine release, allergic responses.

Shared Attributes

  • High Motility: Chemotaxis, transendothelial migration.
  • Phagocytosis: Neutrophils, monocytes, macrophages.
  • Immune Surveillance: Continuous patrolling for pathogens/abnormal cells.
  • Cytokine/Chemokine Production: Orchestrate inflammation and resolution.
  • Tissue Repair: Growth factor release (TGF-β, VEGF, PDGF).

This cellular diversity enables tailored responses to virtually any threat.

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