AML and Cardiac Arrest in Children: A Rare Association Requiring Investigation

Acute Myeloid Leukemia (AML) primarily affects bone marrow and blood. Cardiac arrest is extremely uncommon as a direct manifestation of AML in a 7-year-old. If it occurs, consider:

• Treatment-related cardiotoxicity (anthracyclines)
• Electrolyte emergencies (tumor lysis: hyperkalemia, hypocalcemia)
• Sepsis-induced myocardial depression
• Leukostasis with coronary microthrombi
• Coexisting congenital heart disease

Thorough investigation (ECG, echo, enzymes, electrolytes, blood culture) by pediatric oncology/critical care team is essential.