What are the symptoms of Progeria disease?

Physical symptoms

* Failure to thrive in infancy

* Short stature

* Narrow face with a prominent chin

* Beaked nose

* Receding mandible (lower jaw)

* Delayed or absent puberty

* Osteoporosis (bone loss)

* Joint stiffness

* Limited mobility

* Skin abnormalities, including thin, wrinkled skin, and skin discoloration

Other symptoms

* Cardiovascular problems, including heart defects and stroke

* Kidney problems

* Diabetes mellitus

* Vision problems

* Cognitive and developmental delays

* Speech difficulties

* Hearing loss

* Dental problems

* Gastrointestinal problems

* Sleep apnea

* Frequent infections